Gnotobiotic Mouse Facility

Technical Contact:
Betty Theriault, DVM
Gnotobiotic Mouse Component co-Director
Phone: 773-702-9362

The University of Chicago has a facility in which mice of many different genetic backgrounds are derived as germ-free, having no microbes on or inside of them. These gnotobiotic mice serve as research models that are key in identifying the genes responsible for so many of our disease predispositions and, more importantly, the mechanisms responsible so that we find ways to interfere with progression.

Centralized, germ-free animal care services. We provide both germ-free (axenic, sterile) and gnotobiotic (populated with defined microbiota) animals.

Re-derivation and maintenance of new, germ-free mouse strains.